Material Safety Data Sheet

Print Date:

1.) Picric acid
Synonyms:2, 2,4,6-Trinitrophenyl, 4, 6-Trinitrophenyl, carbazotic acid,

Manufacturer:Sigma Chemical Co.
Street1:PO Box 14508
Street2:
City, State, Zip:St. Louis, Missouri, 63178
Telephone Number:(314) 771-5765
Contact Person:
Title:
Distributer:


2.) Ingredients
Picric acid
  • CAS# 88-89-1
  • Concentration: <1.5%
  • Hazard Classes: Carcinogen, Irritant, Mutagenic, Poison, Sensitizer,


    • Note: See section 16 for any additional information on Ingredients.

    3.) Hazards Identification
    EYE: Irritating SKIN: Readily absorbed through the skin. Can be irritating to the skin. The dust causes sensitization dermatitis usually around the mouth and the sides of the nose. INHALATION: The dust is irritating to the mucous membranes and upper respiratory tract. High concentrations of the dust can cause unconsciousness, weakness, muscle pain and kidney problems. INGESTION: Headache, dizziness, nausea, vomiting and diarrhea. High doses can cause red blood cell damage, liver and kidney damage with blood in the urine.

    4.) First Aid
    Complete an Incident Investigation Report Form if any first aid measures are taken. SKIN EXPOSURE: Immediately wash skin with plenty of water for at least 15 minutes. Call a physician if irritation develops. EYE EXPOSURE: Wash the affected area of the eye for at least 5 minutes using the eye wash station. If an eye wash station isn't available, have the victim lay down, hold the eyelid open and pour water from the inner corner of the eye outward. Cover the eye(s) with dry gauze and then contact the appropriate emergency service for immediate followup. INHALATION: Move to fresh air. If breathing becomes difficult, contact a physician immediately. INGESTION: Rinse out mouth with water provided person is conscious. Immediately call a physician. CLOTHING: Remove contaminated clothing and wash before reuse.

    5.) Fire Fighting
    Extinguising Media:Water Spray, Dry Chemical, Alcohol Foam, Carbon Dioxide

    Firefighting:Small, self-contained fire may be doused using extinguishing media shown above. Larger fires: GET OUT immediately OR wear FULL protective clothing and self- contained breathing apparatus.

    Fire & Explosion Hazards:May explode when heated. In dry form, it is shock sensitive. Emits toxic fumes under fire conditions.

    Upper Explosive Limit:NI
    Lower Explosive Limit:NI
    Flash Point:302F
    Auto-Ignition Temperture:572F

    6.) Cleanup
    Wear rubber gloves and eye goggles. Do not breathe dust. If dry form, moisten the spill with plenty of water. Cover the spill with a 1:1:1 mixture of sodium carbonate, bentonite and sand. Scoop into a container and burn in an incinerator equipped with an afterburner and scrubber.

    7.) Storage and Handling
    Storage:Keep in tightly enclosed container; stored in a cool dry ventilated area.

    Incompatibilities:Strong Oxidants, strong bases, heavy metals, heavy metal salts.

    Hazardous Decomposition:Toxic gasses carbon oxides, nitrogen oxides and sulfur oxides will be released if involved in a fire.

    8.) Exposure Limits/Personal Protection
    Exposure Limits:

    Respiratory Protection:DO NOT breathe dust. Respiratory protection is not required under routine use in the clinical laboratory; wear full face respirator when handling larger quantities.

    Ventilation:When handling dry form, use only in a chemical fume hood or with point of contact ventilation. When in solution, general mechanical ventilation is adequate.

    Protective Gloves:Use polyvinyl alcohol, neoprene or Buna-N gloves

    Eye Protection:Use safety goggles.

    Other:Emergency Eye Bath and quick drench facilities should be maintained in the area of use.

    9.) Physical Data & Usage
    Appearance & Odor:Yellow crystals or liquid; odorless, bitter taste

    Solubility In Water:NI
    Reactivity In Water:NI
    Evaporation Rate:NI
    Volatility:NI
    Vapor Density:7.9
    Vapor Pressure:1@195C
    Boiling Point:NI
    Melting Point:121.8C
    Specific Gravity:1.763

    Usage:component in Bouin's solution.

    Sites:205 Bluff,

    Departments:Histology/Cytology,

    10.) Stability and Reactivity
    Stable:Yes

    Hazardous Polymerization:No

    NFPA: Health = 2 Fire = 4 Reactivity = 4 Specific = -

    11.) Toxicological Information
    IPR mus: LD50 = 563000¼g/kg Experimental mutagen.

    12.) Ecological Information
    None Listed

    13.) Cleanup & Disposal
    Wear rubber gloves and eye goggles. Do not breathe dust. If dry form, moisten the spill with plenty of water. Cover the spill with a 1:1:1 mixture of sodium carbonate, bentonite and sand. Scoop into a container and burn in an incinerator equipped with an afterburner and scrubber.

    14.) Transportation Information
    None Listed

    15.) SARA, CERCLA, RCRA Information

    16.) Additional Information on Ingredients of Picric acid

    Picric acid
  • CAS# 88-89-1
  • Concentration: <1.5%
  • Hazard Classes: Carcinogen, Irritant, Mutagenic, Poison, Sensitizer,
  • Carcinogen: NTP=No , IARC=No , OSHA=Yes
  • Comments: A high explosive in dry form. This chemical is part of a solution. For additional safety information, see safety data for the ingredient itself.